Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro

Diabetes is associated with cardiac metabolic disturbances and increased heart failure risk. Plasma fructose levels are elevated in diabetic patients. A direct role for fructose involvement in diabetic heart pathology has not been investigated. The goals of this study were to clinically evaluate lin...

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Detalhes bibliográficos
Publicado no:Nutr Diabetes
Main Authors: Daniels, Lorna J., Annandale, Marco, Koutsifeli, Parisa, Li, Xun, Bussey, Carol T., van Hout, Isabelle, Bunton, Richard W., Davis, Philip J., Coffey, Sean, Katare, Rajesh, Lamberts, Regis R., Delbridge, Lea M. D., Mellor, Kimberley M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870957/
https://ncbi.nlm.nih.gov/pubmed/33558456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-021-00150-7
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