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Dysregulated Adaptive Immunity Is an Early Event in Liver Cirrhosis Preceding Acute-on-Chronic Liver Failure

INTRODUCTION: Acute-on-chronic liver failure (ACLF) is characterized by high levels of systemic inflammation and parallel suppression of innate immunity, whereas little is known about adaptive immune immunity in ACLF. We therefore aimed to characterize the development of the adaptive immune system d...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Rueschenbaum, Sabrina, Ciesek, Sandra, Queck, Alexander, Widera, Marek, Schwarzkopf, Katharina, Brüne, Bernhard, Welsch, Christoph, Wedemeyer, Heiner, Zeuzem, Stefan, Weigert, Andreas, Lange, Christian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870861/
https://ncbi.nlm.nih.gov/pubmed/33574809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.534731
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