Enhancement of elastin expression by transdermal administration of sialidase isozyme Neu2

Reduction of elastin in the skin causes various skin diseases as well as wrinkles and sagging with aging. Sialidase is a hydrolase that cleaves a sialic acid residue from sialoglycoconjugate. Cleavage of sialic acid from microfibrils by the sialidase isozyme Neu1 facilitates elastic fiber assembly....

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Publicado no:Sci Rep
Main Authors: Minami, Akira, Fujita, Yuka, Goto, Jun, Iuchi, Ayano, Fujita, Kosei, Mikami, Yasuyo, Shiratori, Mako, Ishii, Ami, Mitragotri, Samir, Iwao, Yasunori, Kanazawa, Hiroaki, Kurebayashi, Yuuki, Takahashi, Tadanobu, Otsubo, Tadamune, Ikeda, Kiyoshi, Suzuki, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870814/
https://ncbi.nlm.nih.gov/pubmed/33558588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82820-1
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