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Sex-dependent alterations in behavior, drug responses and dopamine transporter expression in heterozygous DAT-Cre mice

Heterozygous mice that express Cre-recombinase under the dopamine transporter promoter (DAT-Cre knock in mice, or KI) are widely used for targeting midbrain dopamine neurons, under the assumption that their constitutive physiology is not affected. We report here that these mice display striking sex-...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Costa, Kauê Machado, Schenkel, Daniela, Roeper, Jochen
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870653/
https://ncbi.nlm.nih.gov/pubmed/33558587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82600-x
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