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Sex-dependent alterations in behavior, drug responses and dopamine transporter expression in heterozygous DAT-Cre mice

Heterozygous mice that express Cre-recombinase under the dopamine transporter promoter (DAT-Cre knock in mice, or KI) are widely used for targeting midbrain dopamine neurons, under the assumption that their constitutive physiology is not affected. We report here that these mice display striking sex-...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Costa, Kauê Machado, Schenkel, Daniela, Roeper, Jochen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870653/
https://ncbi.nlm.nih.gov/pubmed/33558587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82600-x
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