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Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection

The conversion of auditory and vestibular stimuli into electrical signals is initiated by force transmitted to a mechanotransduction channel through the tip link, a double stranded protein filament held together by two adhesion bonds in the middle. Although thought to form a relatively static struct...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mulhall, Eric M., Ward, Andrew, Yang, Darren, Koussa, Mounir A., Corey, David P., Wong, Wesley P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870652/
https://ncbi.nlm.nih.gov/pubmed/33558532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21033-6
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