Endothelial Dysfunction is Associated with Increased Incidence, Worsened Severity, and Prolonged Duration of Acute Kidney Injury after Severe Trauma

INTRODUCTION: Nearly half of severely injured patients suffer acute kidney injury (AKI), but little is known about its pathogenesis or optimal management. We hypothesized that endothelial dysfunction, evidenced by elevated systemic soluble thrombomodulin (sTM) and syndecan-1, would be associated wit...

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Bibliographic Details
Published in:Shock
Main Authors: Hatton, Gabrielle E., Isbell, Kayla D., Henriksen, Hanne H, Stensballe, Jakob, Brummerstedt, Martin, Johansson, Pär I, Kao, Lillian S., Wade, Charles E.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870558/
https://ncbi.nlm.nih.gov/pubmed/32826819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001638
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