Disease-induced immunomodulation at biomaterial scaffolds detects early pancreatic cancer in a spontaneous model

Pancreatic cancer has the worst prognosis of all cancers due to disease aggressiveness and paucity of early detection platforms. We developed biomaterial scaffolds that recruit metastatic tumor cells and reflect the immune dysregulation of native metastatic sites. While this platform has shown promi...

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Bibliographic Details
Published in:Biomaterials
Main Authors: Bushnell, Grace G., Orbach, Sophia M., Ma, Jeffrey A., Crawford, Howard C., Wicha, Max S., Jeruss, Jacqueline S., Shea, Lonnie D.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870556/
https://ncbi.nlm.nih.gov/pubmed/33418200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120632
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