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Studies on polyethylene glycol-monoclonal antibody conjugates for fabrication of nanoparticles for biomedical applications

OBJECTIVE: The objective of this work is to synthesize and characterize PEGylated monoclonal antibody using the reactivity of oligosaccharide residues in the Fc region of trastuzumab and pertuzumab with a view to preserving their activities. METHODS: The hydrazide-functionalized PEG monomethacrylate...

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Publicado en:J Nanosci Nanomed
Autores principales: Fisusi, Funmilola, Brandy, Nailah, Wu, Jingbo, Akala, Emmanuel O
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869852/
https://ncbi.nlm.nih.gov/pubmed/33564752
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