Chemo-enzymatic synthesis of adenine substituted nicotinic acid adenine dinucleotide phosphate (NAADP) analogs

Nicotinamide adenine dinucleotide phosphate (NADP) is an indispensable metabolic co-substrate and nicotinic acid adenine dinucleotide phosphate (NAADP) is an important Ca(2+) releasing intracellular second messenger. Exploration of the NADP and NAADP interactome often requires the synthesis of NADP...

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Bibliographic Details
Published in:Bioorg Med Chem
Main Authors: Su, Peiling, Bretz, James D., Gunaratne, Gihan S., Marchant, Jonathan S., Walseth, Timothy F., Slama, James T.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869823/
https://ncbi.nlm.nih.gov/pubmed/33321420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115901
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