Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity

Celastrol, a compound extracted from traditional Chinese medicine, has been reported as a potent anti-obesity agent with controversial mechanisms. Here both C57BL/6J and leptin-deficient (ob/ob) mice fed a high-fat diet (HFD) displayed body weight loss after celastrol therapy, opposing the previous...

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Bibliografski detalji
Izdano u:iScience
Glavni autori: Hua, Hu, Zhang, Yue, Zhao, Fei, Chen, Ke, Wu, Tong, Liu, Qianqi, Huang, Songming, Zhang, Aihua, Jia, Zhanjun
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868996/
https://ncbi.nlm.nih.gov/pubmed/33598642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102077
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