Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway

Mounting evidence has demonstrated that microRNA-1224 (miR-1224) is commonly downregulated and serves as a tumor suppressor in multiple malignancies. However, the role and mechanisms responsible for miR-1224 in hepatocellular carcinoma (HCC) remain unclear. In this study, we found that the expressio...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Yang, Shikun, Jiang, Wei, Yang, Wenjie, Yang, Chao, Yang, Xinchen, Chen, Keyan, Hu, Yuanchang, Shen, Gefenqiang, Lu, Ling, Cheng, Feng, Zhang, Feng, Rao, Jianhua, Wang, Xuehao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868928/
https://ncbi.nlm.nih.gov/pubmed/33614242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.01.008
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