Detection of Ca(2+) transients near ryanodine receptors by targeting fluorescent Ca(2+) sensors to the triad

In intact muscle fibers, functional properties of ryanodine receptor (RYR)–mediated sarcoplasmic reticulum (SR) Ca(2+) release triggered by activation of the voltage sensor Ca(V)1.1 have so far essentially been addressed with diffusible Ca(2+)-sensitive dyes. Here, we used a domain (T306) of the pro...

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Vydáno v:J Gen Physiol
Hlavní autoři: Sanchez, Colline, Berthier, Christine, Tourneur, Yves, Monteiro, Laloé, Allard, Bruno, Csernoch, Laszlo, Jacquemond, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868779/
https://ncbi.nlm.nih.gov/pubmed/33538764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012592
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