Adamantane-linked isothiourea derivatives suppress the growth of experimental hepatocellular carcinoma via inhibition of TLR4-MyD88-NF-κB signaling

In this study, in vitro cytotoxic effects of seven adamantyl isothiourea derivatives were evaluated against five human tumor cell lines using the MTT assay. Compounds 5 and 6 were found to be the most active derivatives particularly against hepatocellular carcinoma (HCC). To decipher the potential m...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Hassan, Hanan M, Al-Wahaibi, Lamya H, Shehatou, George SG, El-Emam, Ali A
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868765/
https://ncbi.nlm.nih.gov/pubmed/33575076
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