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Engineering highly efficient backsplicing and translation of synthetic circRNAs
Circular RNAs (circRNAs) are highly stable RNA molecules that are attractive templates for expression of therapeutic proteins and non-coding RNAs. In eukaryotes, circRNAs are primarily generated by the spliceosome through backsplicing. Here, we interrogate different molecular elements including intr...
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| Pubblicato in: | Mol Ther Nucleic Acids |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Gene & Cell Therapy
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7868716/ https://ncbi.nlm.nih.gov/pubmed/33614232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.01.003 |
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