Pivotal Role of TGF-β/Smad Signaling in Cardiac Fibrosis: Non-coding RNAs as Effectual Players

Unintended cardiac fibroblast proliferation in many pathophysiological heart conditions, known as cardiac fibrosis, results in pooling of extracellular matrix (ECM) proteins in the heart muscle. Transforming growth factor β (TGF-β) as a pivotal cytokine/growth factor stimulates fibroblasts and haste...

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Dades bibliogràfiques
Publicat a:Front Cardiovasc Med
Autors principals: Saadat, Somayeh, Noureddini, Mahdi, Mahjoubin-Tehran, Maryam, Nazemi, Sina, Shojaie, Layla, Aschner, Michael, Maleki, Behnaz, Abbasi-kolli, Mohammad, Rajabi Moghadam, Hasan, Alani, Behrang, Mirzaei, Hamed
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Cardiovascular Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868343/
https://ncbi.nlm.nih.gov/pubmed/33569393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2020.588347
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