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Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma with and without Nasal Polyposis: A Post Hoc Analysis of the Phase 2b PATHWAY Study

BACKGROUND: Tezepelumab is a human monoclonal antibody that blocks thymic stromal lymphopoietin, an epithelial cytokine implicated in asthma pathogenesis, from binding to its heterodimeric receptor. In the phase 2b PATHWAY study, tezepelumab significantly reduced annualized asthma exacerbation rates...

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Bibliografiske detaljer
Udgivet i:J Asthma Allergy
Main Authors: Emson, Claire, Corren, Jonathan, Sałapa, Kinga, Hellqvist, Åsa, Parnes, Jane R, Colice, Gene
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868291/
https://ncbi.nlm.nih.gov/pubmed/33568920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JAA.S288260
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