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Hyperosmotic stress alters the RNA Polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression
Stress-induced readthrough transcription results in the synthesis of downstream-of-gene (DoG) containing transcripts. The mechanisms underlying DoG formation during cellular stress remain unknown. Nascent transcription profiles during DoG induction in human cell lines using TT-TimeLapse-seq revealed...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7867636/ https://ncbi.nlm.nih.gov/pubmed/33400923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.12.002 |
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