Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System

Bacterial type II toxin-antitoxin (TA) modules encode a toxic protein that downregulates metabolism and a specific antitoxin that binds and inhibits the toxin during normal growth. In non-typeable Haemophilus influenzae, a common cause of infections in humans, the vapXD locus was found to constitute...

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Publicado en:Structure
Autores principales: Bertelsen, Marie B., Senissar, Meriem, Nielsen, Maja H., Bisiak, Francesco, Cunha, Marta V., Molinaro, Ashley L., Daines, Dayle A., Brodersen, Ditlev E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867571/
https://ncbi.nlm.nih.gov/pubmed/33096014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.10.002
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