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Development of a Single-Step Antibody–Drug Conjugate Purification Process with Membrane Chromatography

Membrane chromatography is routinely used to remove host cell proteins, viral particles, and aggregates during antibody downstream processing. The application of membrane chromatography to the field of antibody-drug conjugates (ADCs) has been applied in a limited capacity and in only specialized sce...

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Foilsithe in:J Clin Med
Main Authors: Cordova, Juan Carlos, Sun, Sheng, Bos, Jeffrey, Thirumalairajan, Srinath, Ghone, Sanjeevani, Hirai, Miyako, Busse, Ricarda A., der Hardt, Julia S. v., Schwartz, Ian, Zhou, Jieyu
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867349/
https://ncbi.nlm.nih.gov/pubmed/33540865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10030552
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