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The lncRNA NEAT1 promotes the epithelial-mesenchymal transition and metastasis of osteosarcoma cells by sponging miR-483 to upregulate STAT3 expression

BACKGROUND: Osteosarcoma is one of the most prevalent primary bone tumours in adolescents. Accumulating evidence shows that aberrant expression of the long non-coding RNA (lncRNA) NEAT1 and microRNA-483 (miR-483) contribute to the epithelial-mesenchymal transition (EMT), invasion and metastasis of t...

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Publicat a:Cancer Cell Int
Autors principals: Chen, Yan, Li, Jun, Xiao, Jia-Kun, Xiao, Lei, Xu, Bin-Wu, Li, Chen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866772/
https://ncbi.nlm.nih.gov/pubmed/33546665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-021-01780-8
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