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Neurometals in the Pathogenesis of Prion Diseases

Prion diseases are progressive and transmissive neurodegenerative diseases. The conformational conversion of normal cellular prion protein (PrP(C)) into abnormal pathogenic prion protein (PrP(Sc)) is critical for its infection and pathogenesis. PrP(C) possesses the ability to bind to various neurome...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Kawahara, Masahiro, Kato-Negishi, Midori, Tanaka, Ken-ichiro
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866166/
https://ncbi.nlm.nih.gov/pubmed/33525334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031267
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