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CD1d-Dependent iNKT Cells Control DSS-Induced Colitis in a Mouse Model of IFNγ-Mediated Hyperinflammation by Increasing IL22-Secreting ILC3 Cells

We have previously shown that CD1d-restricted iNKT cells suppress dysregulated IFNγ expression and intestinal inflammation in Yeti mice on the C57BL/6 background. Since type 3 innate lymphoid cells (ILC3s) in mesenteric lymph nodes (MLN) protect against intestinal inflammation in a CD1d-associated m...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Park, Hyun Jung, Lee, Sung Won, Van Kaer, Luc, Hong, Seokmann
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866066/
https://ncbi.nlm.nih.gov/pubmed/33513946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031250
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