How Should We Test for Lynch Syndrome? A Review of Current Guidelines and Future Strategies

SIMPLE SUMMARY: Carriers of Lynch syndrome (LS) have an increased risk for several types of tumour, in particular bowel and uterine cancers. LS is caused by inheritance of a faulty mismatch repair (MMR) gene, and, in accordance with clinical guidelines, bowel cancers are tested for MMR deficiency to...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Gallon, Richard, Gawthorpe, Peter, Phelps, Rachel L., Hayes, Christine, Borthwick, Gillian M., Santibanez-Koref, Mauro, Jackson, Michael S., Burn, John
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865939/
https://ncbi.nlm.nih.gov/pubmed/33499123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030406
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