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Gene Editing Correction of a Urea Cycle Defect in Organoid Stem Cell Derived Hepatocyte-like Cells

Urea cycle disorders are enzymopathies resulting from inherited deficiencies in any genes of the cycle. In severe cases, currently available therapies are marginally effective, with liver transplantation being the only definitive treatment. Donor liver availability can limit even this therapy. Ident...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Zabulica, Mihaela, Jakobsson, Tomas, Ravaioli, Francesco, Vosough, Massoud, Gramignoli, Roberto, Ellis, Ewa, Rooyackers, Olav, Strom, Stephen C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865883/
https://ncbi.nlm.nih.gov/pubmed/33530582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031217
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