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DPP4 Inhibitor Sitagliptin Enhances Lymphocyte Recruitment and Prolongs Survival in a Syngeneic Ovarian Cancer Mouse Model

SIMPLE SUMMARY: The role of immunity in the development and progression of epithelial ovarian cancer (EOC) is well established. Poor T-cell infiltration is associated with mortality in EOC patients, and recent evidence has suggested that the enzyme DPP4 plays a role in this process. The aim of our s...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Wilson, Amy L., Moffitt, Laura R., Wilson, Kirsty L., Bilandzic, Maree, Wright, Mark D., Gorrell, Mark D., Oehler, Martin K., Plebanski, Magdalena, Stephens, Andrew N.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865851/
https://ncbi.nlm.nih.gov/pubmed/33513866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030487
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