Zoledronate Causes a Systemic Shift of Macrophage Polarization towards M1 In Vivo

Background: Immunomodulatory properties of bisphosphonates (BP) are suggested to contribute to the development of medication-associated osteonecrosis of the jaw (MRONJ). Furthermore, bisphosphonate-derived immune modulation might contribute to the anti-metastatic effect observed in breast cancer pat...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Weber, Manuel, Homm, Andi, Müller, Stefan, Frey, Silke, Amann, Kerstin, Ries, Jutta, Geppert, Carol, Preidl, Raimund, Möst, Tobias, Kämmerer, Peer W., Kesting, Marco, Wehrhan, Falk
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865688/
https://ncbi.nlm.nih.gov/pubmed/33525753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031323
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