Efficacy of early anti-inflammatory treatment with high doses of intravenous anakinra with or without glucocorticoids in patients with severe COVID-19 pneumonia

BACKGROUND: IL-1 plays a pivotal role in the inflammatory response during cytokine storm syndromes. OBJECTIVE: Our aim was to analyze the efficacy and safety of early anti-inflammatory treatment (AIT) with intravenous anakinra with or without glucocorticoids in coronavirus disease 2019 (COVID-19) pn...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Pontali, Emanuele, Volpi, Stefano, Signori, Alessio, Antonucci, Giancarlo, Castellaneta, Marco, Buzzi, Davide, Montale, Amedeo, Bustaffa, Marta, Angelelli, Alessia, Caorsi, Roberta, Giambruno, Elisa, Bobbio, Nicoletta, Feasi, Marcello, Gueli, Ilaria, Tricerri, Francesca, Calautti, Francesca, Castagnola, Elio, Moscatelli, Andrea, Rollandi, Gian Andrea, Ravelli, Angelo, Cassola, Giovanni, Sormani, Maria Pia, Gattorno, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Allergy, Asthma & Immunology 2021
Assuntos:
Covid-19
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865089/
https://ncbi.nlm.nih.gov/pubmed/33556464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2021.01.024
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