Oxidized lipoproteins promote resistance to cancer immunotherapy independent of patient obesity

Anti-tumor immunity is impaired in obese mice. Mechanistic insight into this observation remains sparse and whether it is recapitulated in patients with cancer is unclear because clinical studies have produced conflicting and controversial findings. We addressed this by analyzing data from patients...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Khojandi, Niloufar, Kuehm, Lindsey M., Piening, Alexander, Donlin, Maureen J., Hsueh, Eddy C., Schwartz, Theresa L., Farrell, Kaitlin, Richart, John M., Geerling, Elizabeth, Pinto, Amelia K., George, Sarah L., Albert, Carolyn J., Ford, David A., Chen, Xiufen, Kline, Justin, Teague, Ryan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864876/
https://ncbi.nlm.nih.gov/pubmed/33303575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-20-0358
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