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Exploiting Replication Stress as a Novel Therapeutic Intervention

Ewing sarcoma is an aggressive pediatric tumor of the bone and soft tissue. The current standard of care is radiation and chemotherapy, and patients generally lack targeted therapies. One of the defining molecular features of this tumor type is the presence of significantly elevated levels of replic...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Martin, Jeffrey C., Hoegel, Tamara J., Lynch, Miranda L., Woloszynska, Anna, Melendy, Thomas, Ohm, Joyce E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864862/
https://ncbi.nlm.nih.gov/pubmed/33020173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0651
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