ADNC-RS, a clinical-genetic risk score, predicts Alzheimer’s pathology in autopsy-confirmed Parkinson’s Disease and Dementia with Lewy Bodies

Growing evidence suggests overlap between Alzheimer’s disease (AD) and Parkinson’s disease (PD) pathophysiology in a subset of patients. Indeed, 50–80% of autopsy cases with a primary clinicopathological diagnosis of Lewy body disease (LBD) – most commonly manifesting during life as PD – have concom...

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Veröffentlicht in:Acta Neuropathol
Hauptverfasser: Dai, David L, Tropea, Thomas F, Robinson, John L, Suh, Eunran, Hurtig, Howard, Weintraub, Daniel, Van Deerlin, Vivianna, Lee, Edward B., Trojanowski, John Q, Chen-Plotkin, Alice S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864557/
https://ncbi.nlm.nih.gov/pubmed/32749525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02199-7
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