Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer

Castration-resistant prostate cancer (CRPC) recurs after androgen deprivation therapy (ADT) and is incurable. Reactivation of androgen receptor (AR) signaling in the low androgen environment of ADT drives CRPC. This AR activity occurs through a variety of mechanisms, including up-regulation of AR co...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Zhao, Ning, Peacock, Stephanie O., Lo, Chen Hao, Heidman, Laine M., Rice, Meghan A., Fahrenholtz, Cale D., Greene, Ann M., Magani, Fiorella, Copello, Valeria A., Martinez, Maria Julia, Zhang, Yushan, Daaka, Yehia, Lynch, Conor C., Burnstein, Kerry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864378/
https://ncbi.nlm.nih.gov/pubmed/31243151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw4636
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