Aldose Reductase and the Polyol Pathway in Schwann Cells: Old and New Problems

Aldose reductase (AR) is a member of the reduced nicotinamide adenosine dinucleotide phosphate (NADPH)-dependent aldo-keto reductase superfamily. It is also the rate-limiting enzyme of the polyol pathway, catalyzing the conversion of glucose to sorbitol, which is subsequently converted to fructose b...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Niimi, Naoko, Yako, Hideji, Takaku, Shizuka, Chung, Sookja K., Sango, Kazunori
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864348/
https://ncbi.nlm.nih.gov/pubmed/33494154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031031
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