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Phenotypic Frailty Assessment in Mice: Development, Discoveries, and Experimental Considerations

The underlying mechanisms contributing to the onset of frailty, its progression, and its mortality risk remain unknown. Recently, the two most common human frailty assessments were reverse-translated to mice. Here, we highlight the development of the mouse frailty phenotype, unique discoveries, expe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Physiology (Bethesda)
Hauptverfasser: Baumann, Cory W., Kwak, Dongmin, Thompson, LaDora V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864238/
https://ncbi.nlm.nih.gov/pubmed/33052773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00016.2020
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