In Vitro Systematic Drug Testing Reveals Carboplatin, Paclitaxel, and Alpelisib as a Potential Novel Combination Treatment for Adult Granulosa Cell Tumors

SIMPLE SUMMARY: Granulosa cell tumor treatment is challenging as there are few effective options besides surgery. In this study, we obtained tumor tissue from patients at surgery and cultured tumor cells in the laboratory. After sufficient expansion, we tested the effects of current treatments, such...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Roze, Joline, Sendino Garví, Elena, Stelloo, Ellen, Stangl, Christina, Sereno, Ferdinando, Duran, Karen, Groeneweg, Jolijn, Paijens, Sterre, Nijman, Hans, van Meurs, Hannah, van Lonkhuijzen, Luc, Piek, Jurgen, Lok, Christianne, Jonges, Geertruida, Witteveen, Petronella, Verheijen, René, van Haaften, Gijs, Zweemer, Ronald, Monroe, Glen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864192/
https://ncbi.nlm.nih.gov/pubmed/33498451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030368
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