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Anti-Rheumatic Effect of Antisense Oligonucleotide Cytos-11 Targeting TNF-α Expression

The urgency of the search for inexpensive and effective drugs with localized action for the treatment of rheumatoid arthritis continues unabated. In this study, for the first time we investigated the Cytos-11 antisense oligonucleotide suppression of TNF-α gene expression in a rat model of rheumatoid...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Makalish, Tatyana P., Golovkin, Ilya O., Oberemok, Volodymyr V., Laikova, Kateryna V., Temirova, Zenure Z., Serdyukova, Olesya A., Novikov, Ilya A., Rosovskyi, Roman A., Gordienko, Andrey I., Zyablitskaya, Evgeniya Yu., Gafarova, Elvina A., Yurchenko, Kseniya A., Fomochkina, Iryna I., Kubyshkin, Anatoly V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864158/
https://ncbi.nlm.nih.gov/pubmed/33498456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031022
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