Detection of Inducible Replication-Competent HIV-1 Subtype C Provirus Despite Long-Term Antiretroviral Treatment in Perinatally Infected Adolescents in Botswana

Although antiretroviral therapy (ART) effectively suppresses HIV replication, the latent reservoir remains the barrier to HIV eradication. It remains unknown whether long-term ART impacts levels of inducible replication-competent provirus. To address this knowledge gap, we assessed the proviral rese...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Koofhethile, Catherine K., Moyo, Sikhulile, Kotokwe, Kenanao P., Chang, Charlotte, Mokgethi, Patrick, Muchoba, Lorato, Mokgweetsi, Selebogo, Makhema, Joseph, Lockman, Shahin, Gaseitsiwe, Simani, de Oliveira, Tulio, Essex, M., Shapiro, Roger, Kanki, Phyllis, Novitsky, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Cure/Reservoir
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864094/
https://ncbi.nlm.nih.gov/pubmed/32935556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2020.0097
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