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Pluripotency of embryonic stem cells lacking clathrin-mediated endocytosis cannot be rescued by restoring cellular stiffness

Mouse embryonic stem cells (mESCs) display unique mechanical properties, including low cellular stiffness in contrast to differentiated cells, which are stiffer. We have previously shown that mESCs lacking the clathrin heavy chain (Cltc), an essential component for clathrin-mediated endocytosis (CME...

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Foilsithe in:J Biol Chem
Main Authors: Mote, Ridim D., Yadav, Jyoti, Singh, Surya Bansi, Tiwari, Mahak, V, Shinde Laxmikant, Patil, Shivprasad, Subramanyam, Deepa
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864080/
https://ncbi.nlm.nih.gov/pubmed/33087446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.014343
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