Differential microRNA Expression in USP8-Mutated and Wild-Type Corticotroph Pituitary Tumors Reflect the Difference in Protein Ubiquitination Processes

Background: USP8 mutations are the most common driver changes in corticotroph pituitary tumors. They have direct effect on cells’ proteome through disturbance of ubiquitination process and also influence gene expression. The aim of this study was to compare microRNA profiles in USP8-mutated and wild...

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Vydáno v:J Clin Med
Hlavní autoři: Bujko, Mateusz, Kober, Paulina, Boresowicz, Joanna, Rusetska, Natalia, Zeber-Lubecka, Natalia, Paziewska, Agnieszka, Pekul, Monika, Zielinski, Grzegorz, Styk, Andrzej, Kunicki, Jacek, Ostrowski, Jerzy, Siedlecki, Janusz A, Maksymowicz, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863919/
https://ncbi.nlm.nih.gov/pubmed/33498176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10030375
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