Differential microRNA Expression in USP8-Mutated and Wild-Type Corticotroph Pituitary Tumors Reflect the Difference in Protein Ubiquitination Processes

Background: USP8 mutations are the most common driver changes in corticotroph pituitary tumors. They have direct effect on cells’ proteome through disturbance of ubiquitination process and also influence gene expression. The aim of this study was to compare microRNA profiles in USP8-mutated and wild...

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Bibliografske podrobnosti
izdano v:J Clin Med
Main Authors: Bujko, Mateusz, Kober, Paulina, Boresowicz, Joanna, Rusetska, Natalia, Zeber-Lubecka, Natalia, Paziewska, Agnieszka, Pekul, Monika, Zielinski, Grzegorz, Styk, Andrzej, Kunicki, Jacek, Ostrowski, Jerzy, Siedlecki, Janusz A, Maksymowicz, Maria
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863919/
https://ncbi.nlm.nih.gov/pubmed/33498176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10030375
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