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Ubiquitin-specific Peptidase 8 Regulates the Trafficking and Stability of the Human Organic Anion Transporter 1
BACKGROUND: Organic anion transporter 1 (OAT1) plays a vital role in avoiding the potential toxicity of various anionic drugs through the involvement of kidney elimination. We previously demonstrated that ubiquitin conjugation to OAT1 led to OAT1 internalization from cell surface, followed by degrad...
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| Publicado no: | Biochim Biophys Acta Gen Subj |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7863590/ https://ncbi.nlm.nih.gov/pubmed/32818533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129701 |
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