Bi-allelic amplification of ATM gene in blastoid variant of mantle cell lymphoma: a novel mechanism of inactivation due to chromoanagenesis?

BACKGROUND: Mantle cell lymphoma (MCL) is derived from naïve CD5+ B-cells with the cytogenetic hallmark translocation 11;14. The presence of additional abnormalities is associated with blastoid variants in MCL (BMCL) and confers a poor prognosis. Many of these tumors also show deletion or loss of he...

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Detaylı Bibliyografya
Yayımlandı:Mol Cytogenet
Asıl Yazarlar: Ortega, Veronica, Mendiola, Christina, Rodriguez, Juana, Ehman, William, Qian, You-Wen, Velagaleti, Gopalrao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Case Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863528/
https://ncbi.nlm.nih.gov/pubmed/33541390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-020-00526-x
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