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Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness

Genetic variants account for approximately half the cases of congenital and early‐onset deafness. Methods and technologies for viral delivery of genes into the inner ear have evolved over the past decade to render gene therapy a viable and attractive approach for treatment. Variants in SYNE4, encodi...

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Dettagli Bibliografici
Pubblicato in:EMBO Mol Med
Autori principali: Taiber, Shahar, Cohen, Roie, Yizhar‐Barnea, Ofer, Sprinzak, David, Holt, Jeffrey R, Avraham, Karen B
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863404/
https://ncbi.nlm.nih.gov/pubmed/33350593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013259
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