New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile

BACKGROUND: Aryl-propionic acid derivatives with ibuprofen as representative drug are very important for therapy, being recommended especially for anti-inflammatory and analgesic effects. On other hand 1,3-thiazolidine-4-one scaffold is an important heterocycle, which is associated with different bi...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Vasincu, Ioana-Mirela, Apotrosoaei, Maria, Constantin, Sandra, Butnaru, Maria, Vereștiuc, Liliana, Lupușoru, Cătălina-Elena, Buron, Frederic, Routier, Sylvain, Lupașcu, Dan, Taușer, Roxana-Georgiana, Profire, Lenuța
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863240/
https://ncbi.nlm.nih.gov/pubmed/33541432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-021-00475-0
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