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Anakinra for patients with COVID-19: a meta-analysis of non-randomized cohort studies.

INTRODUCTION: Severe COVID-19 cases have a detrimental hyper-inflammatory host response and different cytokine-blocking biologic agents were explored to improve outcomes. Anakinra blocks the activity of both IL-1α and IL‑1β and is approved for different autoinflammatory disorders, but it is used off...

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Veröffentlicht in:Eur J Intern Med
Hauptverfasser: Pasin, Laura, Cavalli, Giulio, Navalesi, Paolo, Sella, Nicolò, Landoni, Giovanni, Yavorovskiy, Andrey G., Likhvantsev, Valery V., Zangrillo, Alberto, Dagna, Lorenzo, Monti, Giacomo
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Federation of Internal Medicine. Published by Elsevier B.V. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862887/
https://ncbi.nlm.nih.gov/pubmed/33581979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejim.2021.01.016
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