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K(ATP) Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia
PURPOSE: This study aimed to determine the effect of pinacidil, a nonselective K(ATP) channel opener, on diabetes-induced retinal gliosis and inflammation. METHODS: Primary and immortalized cell lines of retinal microglia and Müller cells were used to set up a coculture model. In the trans-well syst...
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| Publicado no: | Invest Ophthalmol Vis Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7862730/ https://ncbi.nlm.nih.gov/pubmed/33523201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.2.3 |
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