טוען...
RNF220 mediates K63-linked polyubiquitination of STAT1 and promotes host defense
STAT1 is a master regulator that orchestrates type 1 and 2 interferon (IFN)-induced IFN-stimulated gene (ISG) expression. The mechanisms by which STAT1 is phosphorylated and activated upon IFN signaling remain elusive. Our work demonstrated that ubiquitination of STAT1 mediated by the E3 ligase RNF2...
שמור ב:
| הוצא לאור ב: | Cell Death Differ |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7862670/ https://ncbi.nlm.nih.gov/pubmed/32814877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00609-7 |
| תגים: |
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