CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes

Generating cardiomyocytes (CMs) from human induced pluripotent stem cells (hiPSCs) has represented a significant advance in our ability to model cardiac disease. Current differentiation protocols, however, have limited use due to their production of heterogenous cell populations, primarily consistin...

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Publicado en:Sci Rep
Autores principales: Chirikian, Orlando, Goodyer, William R., Dzilic, Elda, Serpooshan, Vahid, Buikema, Jan W., McKeithan, Wesley, Wu, HaoDi, Li, Guang, Lee, Soah, Merk, Markus, Galdos, Francisco, Beck, Aimee, Ribeiro, Alexandre J. S., Paige, Sharon, Mercola, Mark, Wu, Joseph C., Pruitt, Beth L., Wu, Sean M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862643/
https://ncbi.nlm.nih.gov/pubmed/33542270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81860-x
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