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Comprehensive characterization and quantification of adeno associated vectors by size exclusion chromatography and multi angle light scattering
Adeno associated virus (AAV) capsids are a leading modality for in vivo gene delivery. Complete and precise characterization of capsid particles, including capsid and vector genome concentration, is necessary to safely and efficaciously dose patients. Size exclusion chromatography (SEC) coupled to m...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7862616/ https://ncbi.nlm.nih.gov/pubmed/33542328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82599-1 |
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