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Megalencephalic Leukoencephalopathy: Insights Into Pathophysiology and Perspectives for Therapy

Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare genetic disorder belonging to the group of vacuolating leukodystrophies. It is characterized by megalencephaly, loss of motor functions, epilepsy, and mild mental decline. In brain biopsies of MLC patients, vacuoles were obse...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Bosch, Assumpció, Estévez, Raúl
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862579/
https://ncbi.nlm.nih.gov/pubmed/33551753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.627887
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