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Acute exercise impacts AhR and PD-1 levels of CD8(+) T-cells—Exploratory results from a randomized cross-over trial comparing endurance versus resistance exercise
PURPOSE: The programmed cell death protein 1 (PD-1) has become a promising target in cancer immunotherapy. PD-1 expression of CD8(+) T-cells may be increased via the exploitation of aryl hydrocarbon receptor (AhR) signaling with kynurenine (KYN) as a ligand. Since exercise affects KYN metabolism, we...
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| Опубликовано в: : | Eur J Appl Physiol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Berlin Heidelberg
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7862188/ https://ncbi.nlm.nih.gov/pubmed/33211154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00421-020-04552-w |
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